The annual Susan G. Komen Race for the Cure, which does so much in the fight against breast cancer, is coming up this weekend. With that, there are some road closures you need to know about.

Beginning at 5 pm Friday and lasting till 11 am Saturday, the 200 block of Polk Street at the 100 & 200 blocks of Vermilion and the 500 & 600 blocks of Jefferson Street will be closed for the event. Detour routes will be made available.